​Laboratory Guide for Lysergamide Identification and Naming


LSD is the classic member of psychedelic lysergamides. Structural modifications to three main regions of the LSD scaffold have resulted in the emergence of new lysergamides entering the novel psychoactive substances (NPS) market.

To support all researchers doing examinations with these drugs, this poster describes the common naming conventions used for lysergamides and presents common lysergamide substitutions, fragments, and tips for mass spectrometry interpretation to help the research community decipher the structure of new lysergamides.

In this guide for lysergamide identification and naming, we review:

  • Common lysergamide substitutions
  • Common lysergamide MS fragments
  • Proposed mechanism for some fragments
  • Mass spectrum of 1P-LSD and tips for interpretation

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